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Toll样受体与树突状细胞 被引量:8

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摘要 树突状细胞是目前已知的功能最强的抗原递呈细胞 ,可通过表达的Toll样受体 (TLR )来识别病原微生物特有的保守成分 ,如脂多糖、细菌DNA中非甲基化的CpG序列和病毒的dsRNA等 ,并通过TLR介导的信号传导通路激活转录因子NF κB和Jun/Fos,引起炎性细胞因子的释放和促进树突状细胞成熟 ,并且可以影响免疫应答的类型。
作者 郝轶群
出处 《上海免疫学杂志》 CSCD 北大核心 2003年第3期212-213,F003,共3页 Shanghai Journal of Immunology
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