脑血栓、心肌梗塞反复发病的血流变、血脂基础

Basis Hemorheology and Serum Lipid of Attack Repetition for Cerebral Thrombosis and Myocardial Infarction

目的 探讨个体 12年的血流变、血脂波动范围及两者长期处于高值对脑血栓、心肌梗塞多次复发的作用。方法 分类统计 12年的测定结果。比较急性期和间隔期及正常参考值三者之间的差异。 8次急性期的测定结果分为第一组 ( 1- 4次 )和第二组 ( 5 - 8次 )计算均值并比较差异。结果 间隔期与正常参考值比较 ,ESR、HDL c无显著性差异 (P >0 .0 5 ) ,血浆粘度有显著性差异 (P <0 .0 5 ) ,其他指标均有非常显著性差异 (P <0 .0 1)。急性期与间隔期比较 ,除HDL c外指标均值都偏高 ,但无显著性差异。急性期除TG和ESR外 ,第二组均值较第一组有所降低。急性期指标不是患者自身的最高值 ,但平均值、最低值都高于间隔期 ,除TC外未超出正常参考值上限。结论 血流变、血脂长期处于高值是该病人脑血栓或心肌梗塞多次发病的血液学主要因素 ,尤以血清TC增高最为明显。了解自身的血流变、血脂波动范围有临床意义。

Objective To study the fluctuate range of hemorheology and serum lipid, the relation of high hemorheology and serum lipid in cerebral thrombosis and myocardial infarction to in repetition in a patient for 12 years. Methods Count the result of hemorheology and serum lipid for 12 years,and compare the difference of results among acute-period, interrupt-period and normal values, and the average values of two groups on acute- period. Results Interrupt period and normal values had significant difference (P<0.01 or P<0.05) except the ESR and DHL-C (P>0.05). No difference between acute period and interrupt period. The 2nd group average values are lower than the 1st's except TG and ESR in acute period. The parameters of acute period are not the highest of the patient's, average values and the lowest values of acute period's are higher than interrupt periods, but they are not over the x+2s of normal value except TC. Conclusion It is major factor that hemorheology and serum lipid are higher for long time in cerebral thrombosis and myocardial infarction. High-TC is major factor. It is valuable to get parameter change of hemorheology and serum lipid in patient.