玄冬冲剂的制备及临床应用

Preparation and Clinical Application of Xuandong Granules

目的 :研制玄冬冲剂并观察对急性咽炎的治疗效果。方法 :采用提取浓缩工艺制备玄冬冲剂 ,并将门诊患急性咽炎的病人 178例随机分为玄冬冲剂治疗组 118例和清热散结片对照组 6 0例 ,治疗 1个疗程 ,观察疗效。结果 :制定玄冬冲剂的制备工艺和质量标准 ;治疗组显效 73例 ,有效 39例 ,无效 6例 ,临床总有效率 94 .9% ;对照组显效 2 0例 ,有效 2 4例 ,无效 6例 ,临床总有效率 73.3%。两组疗效比较 ,有极显著性差异 (P <0 .0 0 1)。结论 :玄冬冲剂配方合理 ,质量可靠 ,适用于治疗急性咽炎 ,未发现任何不良反应。

Objective: To study the preparation and application of Xuandong granules.Method: Xuandong granules was gained by concentrating technique; and 178 patients with acute pharyngitis were randomly divided into Xuandong group (118 patients) and controlled group (60 patients) administrated with Qingresanjie tablets. Result: The preparation technique and the quality standard of Xuandong qranules. The total efficiency rate in Xuandong group was 94.9%, and no adverse reaction was found; while the total efficiency rate was in the controlled group 73.3% .The difference was significant ( χ 2 = 17.1 , P < 0.01 ).Conclusion: The preparation of the solution is feasible. The product is stable and has obvious effect for the clinic.