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右美托咪定与咪芬合剂防治七氟烷麻醉苏醒期躁动的比较研究

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摘要 目的 :比较右美托咪定与咪芬合剂(咪达唑仑+芬太尼)防治七氟烷麻醉苏醒期躁动的效果。方法 :气管插管全麻下行腹腔镜胃癌根治术或直(结)肠癌根治手术患者共46例,随机数字表法分为右美托咪定组(D组)和咪芬合剂组(MF组),每组各23例。手术结束前40 min,D组静脉泵注右美托咪定0.5μg/kg(泵注10 min),MF组泵注咪达唑仑0.03 mg/kg+芬太尼1.5μg/kg(泵注10 min),调控麻醉期间患者血压波动范围在基础血压20%之内。记录苏醒时间、拔管时间和苏醒期躁动评分。结果:MF组苏醒时间为(18.69±6.36)min,拔管时间为(26.13±6.83)min,均长于D组的(15.01±3.85)min和(18.74±3.80)min(P<0.05);而躁动评分两组间差异无统计学意义(P>0.05)。结论 :右美托咪定与咪芬合剂均可防治七氟烷麻醉苏醒期躁动,右美托咪定优于咪芬合剂。
出处 《南通大学学报(医学版)》 2015年第4期293-294,共2页 Journal of Nantong University(Medical sciences)
基金 国家自然科学青年基金资助项目(81300949) 江苏省自然科学青年基金资助项目(BK2012102)
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