血管紧张素Ⅱ的生物学效应及中药对其影响

The Bioactivity of AngiotensinⅡand the Effects of Related Chinese Herbs

目的 :对血管紧张素Ⅱ的生物效应及相关中药对其影响的资料进行综述。方法 :对近年国内外相关文献进行归纳、介绍。结果 :血管紧张素Ⅱ对许多疾病的发生和发展起重大影响 ,如 :高血压 ,动脉粥样硬化 ,心肌缺血再灌流损伤 ,心室肥厚及心肌纤维化 ,纤溶系统活性下降和血栓形成 ,肾功能损害和组织纤维化等。有些中药具有抗血管紧张素Ⅱ作用。结论

Objective: To review the bioactivity of angiotensin Ⅱand the effects of Chinese herbs on it. Method: The correlative documents published in recent years were summarized. Result: AngiotensinⅡplays an important role in the development of many diseases, such as hypertension, arteriosclerosis, myocardial lesion due to ischemia and reperfusion, cardiac hypertrophy and fibrosis, dysfunction of fibrinolytic system, thrombosis, renal failure etc. Some Chinese herbs inhibit the actions of angiotensin Ⅱ. Conclusion: Further researches must be done to investigate the bioactivity of angiotensin II and the effects of Chinese herbs on preventing the body tissue from being impaired by it.