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细胞因子聚乙二醇修饰物的研究进展 被引量:2

Research progress on polyethylene glycol-modified cytokine
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摘要 目的 综述细胞因子聚乙二醇 (PEG)修饰物的研究进展。方法 通过查阅近年来国内外的相关文献 ,从制备、产物稳定性及药物动力学等方面进行了总结。结果与结论 细胞因子聚乙二醇修饰物的稳定性与体内药动学特性均有改善 ,其生物活性的发挥则受多种因素的影响 ,但可通过定点选择性修饰。
出处 《中国药学杂志》 CAS CSCD 北大核心 2003年第5期325-328,共4页 Chinese Pharmaceutical Journal
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