亚低温治疗颅脑损伤C反应蛋白的变化

CRP change in craniocerebral injury after hypothermia treatment

目的 研究亚低温治疗颅脑损伤后血清C反应蛋白 (CRP)水平的变化。方法 通过对 40例颅脑损伤动物模型亚低温与非亚低温治疗后血清CRP水平的变化 ,比较其治疗效果。结果 常温组脑组织含水量为 ( 80 .3 6± 0 .86) % ,血清CRP水平为 ( 4 2 .3 5± 6.40 )mg/L ;亚低温治疗组脑组织含水量为 ( 77.43± 0 .3 9) % ,血清CRP水平为 ( 3 8.46± 8.43 )mg/L ,差异存在显著性 (P <0 .0 1)。结论 提示亚低温对治疗颅脑损伤有明显的治疗作用。

Objective To study the C reactive protein (CRP) change in craniocerebral injury after hypothermia treatment.Methods A comparison was made on the change of CRP levels between the hypothermia group and non-hypothermia group of animal models of cerebrocranial injury.Results The water contents in brain tissue of non-hypothermia and hypothermia models were (80.36±0.86)% and (77.43±0.39)% respectively; CRP levels in the non-hypothermia and hypothermia group were (42.35±6.40) mg/L and (38.46±8.43) mg/L respectively.There was significant difference between two groups ( P <0.01).Conclusion Hypothermia was evidently helpful for treatment in brain injury.