丝裂霉素C及可调整缝线在小梁切除术中的应用

Use of mitomycin C and adjustable sutures in trabeculectomy.

目的 观察丝裂霉素C联合可调整缝线在青光眼小梁切除术中应用的效果。方法 我院近3年来小梁切除术98例,术中采用巩膜瓣下放置含丝裂霉素C棉片2～5分钟,然后迅速以平衡盐溶液冲洗,切除2mm×3mm包括小梁在内的深层角巩膜缘组织,并做虹膜根部切除,用10-0尼龙线间断缝合巩膜瓣2～4针后,再于巩膜瓣一侧或两侧作1条或2条型巩膜瓣缝合。形成前房。术后2周、3月、1年及1.5年检查视力、眼压、前房、滤过泡等情况。结果 术后眼压控制良好,Ⅰ、Ⅱ度浅前房发生率低,滤过泡形成良好,43％视力保持不变或改善,炎症反应轻,并发症少。结论 丝裂霉素C可提高小梁切除术后眼压控制率,联合可调整缝线,可有效控制术后滤过水平,减少术后并发症,提高成功率。

Objective To observe the effect of mitomycin C and adjustable sutures in trabeculectomy for glaucoma. Methods In the last 3 years, 98 cases of glaucoma received trabeculectomy, during surgery mitomycin C and adjustable sutures were used for the control of intraocular pressure (IOP) .Visual acuity, IOP, anterior chamber and filtering bleb were observed at 2 weeks, 3 months, 1 year and 1 and half years after surgery. Results After surgery, IOP was controlled well, the rate of shallow anterior was low and filtering bleb formed in most cases, visual acuity remained unchanged or improved in 43% eyes. Conclusion Mitomycin C combined adjustable sutures can improve the successful rate of tra-beculeetomy and reduce the surgical complications at the same time.