小儿热性惊厥174例临床与复发因素分析

Analysis of clinical features and factors of rrecurrence in 174 cchildren with ffebrile sseizures

目的探讨儿童首次热性惊厥(FC)发生及可能引起复发的相关危险因素。方法收集FC首次发作就诊住院患儿174例,对其首次发作年龄、性别、诱发疾病、发作时体温、发作次数、惊厥持续时间、头颅CT检查等进行观察,并跟踪随访3～5年(随访率为87.36%),对可能影响复发的11种临床因素进行统计学分析。结果 FC首次发病多见于6月龄～4岁儿童,男性发病多于女性,上呼吸道感染为其最常见的诱发疾病(80.46%),头颅CT检查均正常。与FC复发可能的相关危险因素为首次发作年龄、体温、发作次数、惊厥持续时间、复杂性FC、家族惊厥史、围生期异常、剖宫产等。结论 FC的发生与年龄、性别相关,上呼吸道感染为其最常见的诱发疾病。首次FC年龄、体温、发作次数、惊厥持续时间、复杂性FC、家族惊厥史、围生期异常、剖宫产等临床因素与FC复发有关。

Objective To investigate risk factors for the onset and recurrence of febrile convulsions(FC) in children.Methods 174 children with first attack of FC hospitalized were collected.Their age,gender,inducing diseases,body temperature,number of episodes,duration of the seizures and cranial CT examination at onset were observed and followed up for 3 to 5 years(follow-up rate 87.36%).11 clinical factors which might affect the recurrence were statistically analyzed.Results The onset of FC was usually in children between 6 months to 4 years old and was more common in boys.The most common factor was upper respiratory tract infection(80.46%).Cranial CT examinations were normal in all patients.Possible risk factors for recurrence of FC were age,body temperature,the number of attacks,seizure duration,complex FC at onset,as well as family history of seizures,Perinatal abnormalities and abdominal delivery.Conclusion The occurrence of FC is related to age and gender and its most common factor is upper respiratory tract infection.Age,body temperature,the number of attacks,seizure duration,complex FC at onset,as well as family history of seizures,perinatal abnormalities and abdominal delivery are related with the recurrence of FC.