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加巴喷丁胶囊联合窄谱UVB治疗老年性皮肤瘙痒症疗效观察 被引量:2

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摘要 目的探讨加巴喷丁胶囊联合窄谱UVB治疗老年性皮肤瘙痒症的临床疗效及安全性。方法将78例老年性皮肤瘙痒症患者分为3组,治疗组30例,口服加巴喷丁胶囊0.3 g/晚,窄谱UVB照射每周2次;对照Ⅰ组24例,仅口服加巴喷丁胶囊0.3 g/晚;对照Ⅱ组24例给予窄谱UVB照射每周2次,口服氯雷他定片10 mg/晚。所有患者均外用薇诺娜保湿修护霜,疗程为2周。分析各组患者治疗前后瘙痒程度评分、皮肤病生活质量指数(DLQI)变化及临床疗效判定。结果治疗2周后治疗组治疗总积分与对照Ⅰ组、对照Ⅱ组比较差异均有统计学意义(t=2.94、2.23,P<0.05);治疗组有效率为86.67%;对照Ⅰ组、对照Ⅱ组治疗有效率分别为62.50%、45.83%,治疗组与对照组有效率比较差异有统计学意义(χ~2=8.60、4.26,P<0.05)。治疗过程中,3例患者服用加巴喷丁胶囊出现嗜睡、头痛、轻度恶心症状,但可耐受,继续服药后症状自行缓解。结论加巴喷丁胶囊联合窄谱UVB治疗老年性皮肤瘙痒症,疗效确切,安全。
出处 《宁夏医学杂志》 CAS 2019年第5期460-462,共3页 Ningxia Medical Journal
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