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食管动力及24 h食管pH测定在食管源性胸痛患者中的临床应用 被引量:6

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摘要 目的探讨食管动力及24 h食管pH测定在食管源性胸痛患者中的临床应用。方法收集52例考虑食管源性胸痛患者的病例资料,进行食管动力及24 h食管pH测定,以指导临床诊断及治疗。结果 24 h食管pH测定结果显示,25例(48.08%)存在异常酸反流;食管动力测定异常者29例(55.77%),食管下段括约肌压力(LESP)降低20例(38.5%)、松弛不良5例(9.6%)、LESP升高4例(7.7%)。经食管动力及24 h食管pH测定,诊断为胃食管反流病23例,食管裂孔疝2例,功能性胸痛15例,非特异性食管运动障碍10例,弥漫性食管痉挛1例,贲门失弛缓1例。24 h食管pH及食管动力测定对食管源性胸痛患者的阳性检出率分别为48.08%和55.77%,均高于内镜检查,差异有统计学意义(P<0.05)。结论食管动力及24 h食管pH测定对食管源性胸痛患者的临床诊断具有一定的指导价值,尤其是对内镜阴性的食管源性胸痛具有较好的诊断价值。
出处 《宁夏医学杂志》 CAS 2019年第9期833-835,共3页 Ningxia Medical Journal
基金 宁夏医科大学基金项目(XY2017176)
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  • 1Hoshino M,Sundaram A,Mittal SK. Role of the lower esophageal sphincter on acid exposure revisited with high-resolution manometry[J].{H}Journal of the American College of Surgeons,2011,(06):743-750.
  • 2Pandolfino JE,Zhang QG,Ghosh SK. Transient lower esophageal sphincter relaxations and reflux:mechanistic analysis using concurrent fluoroscopy and high-resolution manometry[J].{H}GASTROENTEROLOGY,2006,(06):1725-1733.
  • 3Hoppo T,Komatsu Y,Nieponice A. Toward an improved understanding of isolated upright reflux:positional effects on the lower esophageal sphincter in patients with symptoms of gastroesophageal reflux[J].{H}WORLD Journal OF SURGERY,2012,(07):1623-1631.
  • 4Nwokediuko SC. Current trends in the management of gastroesophageal reflux disease:a review[J].ISRN Gastroenterol,2012.391631.
  • 5Babaei A,Bhargava V,Korsapati H. A unique longitudinal muscle contraction pattern associated with transient lower esophageal sphincter relaxation[J].{H}GASTROENTEROLOGY,2008,(05):1322-1331.
  • 6Shukla A,Meshram M,Gopan A. Ingestion of a carbonated beverage decreases lower esophageal sphincter pressure and increases frequency of transient lower esophageal sphincter relaxation in normal subjects[J].{H}Indian Journal of Gastroenterology,2012,(03):121-124.
  • 7van Wijk MP,Blackshaw LA,Dent J. Distension of the esophagogastric junction augments triggering of transient lower esophageal sphincter relaxation[J].{H}American Journal of Physiology Gastrointestinal and Liver Physiology,2011,(04):G713-G718.
  • 8Kahrilas PJ,Shi G,Manka M. Increased frequency of transient lower esophageal sphincter relaxation induced by gastric distention in reflux patients with hiatal hernia[J].{H}GASTROENTEROLOGY,2000,(04):688-695.
  • 9Jirholt J,Asling B,Hammond P. 4-aminobutyrate aminotransferase(ABAT):genetic and pharmacological evidence for an involvement in gastro esophageal reflux disease[J].PLoS One,2011,(04):e19095.
  • 10Beaumont H,Bennink RJ,de Jong J. The position of the acid pocket as a major risk factor for acidic reflux in healthy subjects and patients with GORD[J].{H}GUT,2010,(04):441-451.

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