环戊-2-烯酮的研究 Ⅰ.环戊-2-烯酮与醛反应的区域选择及非对映立体选择性

Studies on Cyclopent-2-enone Ⅰ. The Region-and Diastereoselectivities of Aldol Reaction of Cyclopent-2-enone and Aldehydes

本文系统研究了环戊-2-烯酮在碱性条件下与醛类的羟醛缩合反应,并通过结构及过渡状态的分析,解释了所得的这类反应的区域及非对映立体选择性.

The a Idol reaction of cyclopent-2-enone with aldehydes under base conditions has been systematically studied. The obtained region-and diastereoselectivities has been explained by structure and transition state analysis.