男性中青年缺血性卒中患者病因及危险因素分析

Analysis on Cause and Risk Factors of Ischemic Stroke in Young and Middle-aged Male

目的:探讨男性中青年缺血性卒中的不同病因及危险因素。方法:挑选20-45岁男性缺血性卒中患者72例,按年龄分成两组。20-29岁1组,30-45岁1组。再根据TOAST病因分类,将患者分成5组(ATR、CEMB、LAC、OTH、UND)。结果:72例男性缺血性卒中患者中,根据TOAST病因分类,ATR17例,LAC30例,CEMB6例,OTH10例,UND9例。讨论:男性中青年中病因复杂,20-29岁组,其它原因所致脑梗死(LAC)和不明原因脑梗死(UND)多见,30-45岁组腔隙性脑梗死(LAC)和大动脉粥样硬化(ATR)多见,其中,高血压、高血糖、高血脂、肥胖、吸烟、酗酒、高同型半胱氨酸血症、高尿酸血症、睡眠呼吸暂停综合征、血管病家族史是男性中青年缺血性卒中的重要危险因素。

Objective:To explore the causes and risk factors of ischemic stroke in young and middle-aged male. Method:72 male (20-45 years old) with ischemic stroke were randomly divided into two groups,one group was aged between 20-29 years old,and the other group was aged between 30-45 years old. Then divided them into five groups according to the TOAST (ATR,CEMB,LAC,OTH and UND). Result: According to TOAST pathogen,there were 17 cases of ATR,30 cases of LAC,6 cases of CEMB,10 cases of OTH,and 9 cases of UND.Conclusion: Ischemic stroke in young and middle-aged male has complex etiological factor. LAC and UND are common in group aged between 20-29 years old,LAC and ATR are common in group aged between 30-45. Hypertension,hyperglycemia,hyperlipidemia,obesity,smoke,excessive drinking,hyperhomocysteinemia,hyperuricemia,sleep apnea syndrome,vascular disease family history are the important risk factors of ischemic stroke in young and middle-aged male.