摘要
目的:观察前列地尔注射液治疗慢性肾功能衰竭的临床疗效。方法:选择40例均未透析慢性肾衰竭住院患者在常规用药基础上给予前列地尔注射液10ug,每天1次,疗程10～14天,观察治疗前后血尿素氮(BUN)、血肌酐(SCr)、肌酐清除率(Ccr)和24小时尿蛋白定量变化。结果:治疗后血尿素氮(BUN)、血肌酐(SCr)较治疗前明显下降(p【0.01),肌酐清除率(Ccr)较治疗前明显上升(P【0.01),24小时尿蛋白定量较治疗前明显减少(P【0.01)。结论:前列地尔注射液有利于减缓慢性肾衰的进展。
Objective:To observe the clinical efficacy of injection of alprostadil in the treatment of chronic renal failure . Methods: 40 cases of non-dialysis chronic renal failure patients with conventional drugs given 10ug alprostadil once a day, 10-14 days as a course, contrast the concentration of the blood urea nitrogen (BUN), creatinine (SCr), creatinine clearance rate(Ccr), 24-hour urinary protein before and after the treatment. Results:The blood urea nitrogen (BUN), serum creatinine (SCr) decreased significantly than prior treatment (p<0.01), creatinine clearance rate (Ccr) increased significantly than prior treatment (P<0.01), 24 hours urinary protein reduced significantly than the pre-treatment (P<0.01). Conclusion:alprostadil may prevent the progression of chronic renal failure .
出处
《内蒙古中医药》
2009年第3X期62-63,共2页
Inner Mongolia Journal of Traditional Chinese Medicine
关键词
前列地尔
肾功能衰竭
Alprostadil
renal failure
chronic
