早期肠道内营养对重型颅脑损伤致应激性溃疡出血的影响

The impact of Early enteral nutrition for Severe craniocerebral injury caused by Stress ulcer bleeding

目的:探讨预防重型颅脑损伤致应激性溃疡出血的方法。方法:将72例重型颅脑损伤患者随机分为甲乙两组:甲组对患者进行早期肠道内营养,乙组对患者进行周围静脉营养。动态观察其体重的变化及应激性溃疡出血的发生。结果:伤后14天,甲组体重减轻平均为2.4kg,乙组体重减轻平均在8.5kg;应激性溃疡出血发生率,甲组为5例,乙组为12例。结论:重型颅脑损伤后早期进行肠道内营养的患者应激性溃疡出血的发生率明显低于实行周围脉营养患者。对重型颅脑损伤患者早期进行肠道内营养,可有效地维持胃肠道功能、中和胃酸,维持胃肠内正常PH值。可促进胃肠道激素分泌,促进胃肠黏膜生长及剌激黏膜细胞的更新,直接和间接地维持胃肠道的生态平衡,保护胃肠道结构的正常状态,提高机体免疫力。在降低应激性溃疡出血(SU)的发生方面有着重要的意义。

Objective: Discuss the method of the prevention for Severe craniocerebral injury caused by Stress ulcer bleeding. Methods: 72 patients with Severe craniocerebral injury caused by stress ulcer bleeding were randomly divided into two equal groups. For A group patients provide with early enteral nutrition.For B group patients provide Peripheral parenteral nutrition. Dynamic observed its body weight change and the occurrence of Stress ulcer bleeding. Results :Group A lost weight 2.4kg equally after 14 days but group B lost weight 8.5kg. The incidence of Stress ulcer bleeding or group A was 5 patients and group B was 12 patients. Conclusion : The incidence of Stress ulcer bleeding was significantly lower than patients implements of nutrition in peripheral vein,after early enteral nutrition for Severe craniocerebral injury. For patients with severe craniocerebral injury early intestinal nutrition, can maintain gastrointestinal function effectively, as well as improve immunity. It has the important significance to decrease incidence rate of ulcer bleeding (SU).