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18例胃肠道原发性弥漫大B细胞淋巴瘤的分型探讨

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摘要 目的:探讨胃肠道原发性弥漫性大B细胞淋巴瘤的分型与临床病理的关系。方法:采用免疫组化法标记18例胃肠道原发性弥漫大B细胞淋巴瘤中MUM-1、bcl-6、CD10、bcl-2、Ki-67的表达。结果:18例胃肠道原发性弥漫大B细胞淋巴瘤中,8例为生发中心细胞来源的即生发中心样型(GCB),10例为生发中心后B细胞来源即非生发中心样型(非GCB)。非GCB型的增值活性与GCB型相似;GCB和非GCB型中bcl-2表达的阳性率分别为50%和70%。结论:胃肠道原发性弥漫大B细胞淋巴瘤以非GCB型多见,预后差。
作者 孔玉莲
出处 《内蒙古中医药》 2009年第11X期56-57,共2页 Inner Mongolia Journal of Traditional Chinese Medicine
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