体检人群中踝臂指数特点分析

Study on Ankle-Brachial Index in Physical Examination Population

目的:了解体检人群中踝臂指数(ABI)的临床特点。方法:体检人群资料共计949例(女203),年龄46.12±11.23岁,使用日本科林动脉硬化测定仪(型号BP～203RPEⅡvp-100)测定ABI。并检测血总胆固醇(TC)、血甘油三脂(TG)、高密度脂蛋白(HDL)、低密度脂蛋白(LDL)、血糖(GLU)、血尿酸(UA)、肝肾功能及体重指数。作均数比较、t检验,简单相关分析,多因素相关分析,逐步回归分析。结果:在体检人群中ABI平均为1.06±0.08,为正态分布,ABI<0.9有15例,其ABI异常检出率为1.58%。他们的主要特点为年龄轻(29.40±6.08岁),且没有常见的心血管病危险因素聚集,随访近1年没有发生未发生外周血管疾病和心血管疾病。多元回归分析,影响ABI的主要因素是年龄,其次是高血压病史。结论:在体检人群中ABI呈正态分布,仅与年龄和高血压病史成正相关。对没有心血管病危险因素的年轻人群中ABI<0.9的临床意义要进一步评估。

Objective: The aim of this study is to determin the clinical characteristics of Ankle-Brachial Index (ABI) in physical examination population. Methods: 949 cases of physical examination population were choosen, including 203 females, with ages from 46.12±11.23 (years old). ABI was measured on the Japan's Kolin Arteriosclerosis Insturment, (model: BP-203RPE Ⅱ vp-100). Serum total cholesterol(TC), triglyceride (TG), high density lipoprotein (HDL), low density lipoprotein (LDL), blood glucose (GLU), uric acid, liver and kidney function and body mass index were also determined. Means Comparison, T Test, Simple Correlation Analysis, Multivariate Analysis and Stepwise Regression Analysis were performed. Results: The average ABI value is 1.06±0.08 and meet the normal distribution. 15 cases had an ABI less than 0.9 and the ABI Abnormality rate is 1.58%, These people are very young (ages from 29.40±6.08), with no risk factors of common cardiovascular diseases. No peripheral vascular disease or cardiovascular disease were occurred in these patients during one year's follow-up. The factors of ages and hypotension histories as well were found using Multiple Regression Analysis to influence ABI. Conclusion: ABI in physical examination population were under normal distribution and was only positively correlation with ages and hypotension histories. Further studies are still required to investigate the clinical significance of ABI<0.9 among young people.