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MMPs/TIMPs、TGF-β_1、细胞外基质与糖尿病肾病 被引量:7

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摘要 转化生长因子 β1 可刺激系膜细胞外基质 (ECM)蛋白的合成 ,抑制基质金属蛋白酶的酶解活性 ,并增加其抑制剂组织型金属蛋白酶抑制剂的活性 ,从而促进ECM的沉积 。
出处 《国外医学(内分泌学分册)》 2003年第3期201-203,共3页 Foreign Medical Sciences(Section of Endocrinology)
基金 沈阳市科学技术基金 (2 0 0 0 5 0 0 39)
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