抵抗素的研究现状
摘要
抵抗素是脂肪细胞分泌的一种多肽类信号分子 ,它能拮抗胰岛素的作用 ,在肥胖导致的胰岛素抵抗中发挥作用 ,被认为是联系肥胖和 2型糖尿病的纽带。它的发现对于肥胖症和
出处
《国外医学（内分泌学分册）》
2003年第3期206-208,共3页
Foreign Medical Sciences(Section of Endocrinology)
参考文献16
-
1Kim K H, Lee K, Moon Y S, et al. A Cysteine-rich adipose tissue-specific secretory factor inhibits adipocyte differentiation[ J]. J Biol Chem, 2001,276 : 11252-11256.
-
2Steppan C M, Bailey S T, Bhat S, et al. The hormone resistin links obesity to diabetes[J]. Nature,2001,409:307-312.
-
3Holeomb I N, Kabakoff R C, Chan B, et al. FIZZ1, a novel Cysteine-rich secreted protein associated with pulmonary inflammation, defines a new gene family[J] . Embol J,2000,19:4046-4055.
-
4Steppan M, Brown E J, Wright C M. A family of tissue-specific resistin-like molecules [J]. Proc Natl Acad Sci USA, 2001,98 : 502-506.
-
5Lay S L, Boucher J, Rey A, et al. Decreased resistin expression in mice with different sensitivities to a high-fat diet[J]. Biochem Biophys Res Commun,2001,289:564-567.
-
6Way J M, Gorgun C Z, Tong Q, et al. Adipose tissue resistin expression is severely suppressed in obesity and stimulated by peroxisome proliferator-activated receptorγ- agonists[J]. J Biol Chem, 2001,276:25651-25653.
-
7Patel L, Buckels A C, Kinghorn I J, et al. Resistin is expressed in human macrophages and directly regulated by PPAR gamma activators [ J ]. Biochem Biophys Res Commun, 2003,300:472-476.
-
8Martinez J A, Margareto J, Marti A, et al. Resistin overexpression is induced by a beta3 adrenergic agonist in diet-related overweightness [ J ]. J Physiol Biochem, 2001,57 : 287-288.
-
9Fasshauer M, Klein J, Neumann S, et al. Isoproterenol inhibits resistin gene expression through a GS-protein-coupled pathway in 3T3-L1 adipocytes[J]. FEBS Lett, 2001,500:60-63.
-
10Spiegelman B M, Flier J S. Obesity and the regulation of energy balance [ J ]. Cell, 2001,104 : 531-543.
-
1周强,罗淼珊,吕家春,康格非.抵抗素在肥胖及2型糖尿病中的研究进展[J].国际检验医学杂志,2008,29(4):333-335. 被引量：3
-
2方燕兰,梁黎.对抵抗素在肥胖性胰岛素抵抗中作用及作用机制的争议[J].国际内分泌代谢杂志,2006,26(1):26-28.
-
3汪永生,王连生.内脏脂肪素与糖代谢及血管性疾病的研究进展[J].心血管病学进展,2011,32(3):401-405. 被引量：3
-
4梁梅花,张巾超,刘枫晨,刘燕,李强.血清resistin与单纯肥胖或代谢综合征的关系[J].哈尔滨医科大学学报,2008,42(1):60-62. 被引量：3
-
5张力文.切断糖尿病与癌症的“纽带”[J].糖尿病天地,2015,0(3):30-30.
-
6王娜,唐彬,董砚虎.2型糖尿病与激素的研究进展[J].国外医学（内分泌学分册）,2003,23(6):422-424. 被引量：1
-
7毛红仙,汪大望.瘦素、抵抗素是联系肥胖与糖代谢异常和脂代谢异常的纽带和桥梁吗?[J].浙江医学,2003,25(5):319-321. 被引量：2
-
8张景岚,周广朋.2型糖尿病胰岛素抵抗与RBP4、游离脂肪酸临床相关研究[J].四川医学,2016,37(9):960-962. 被引量：12
-
9于荣波,苏丽清.糖耐量减低患者血清脂联素与HsCRP、TNF-α、IL-6相关性研究[J].山东医药,2007,47(28):42-43.
-
10吴颖,高晓明.瘦素与自身免疫疾病[J].第二军医大学学报,2002,23(10):1061-1062. 被引量：3
