摘要
关地木通的肾毒性在国内外引起了极大关注。本文对关木通进行了本草学考证,并对关木通肾脏损害的临床特点以及近年来在动物模型、毒性机理和药代动力学等方面的实验研究进行了综述。
The nephrotoxicity of Caulis Aristolochiae Manshuriensis has got more and more attention in China and abroad. This article makes the textual research of Caulis Aristolochiae Manshuriensis from the viewpoint of herbalism and summarizes the clinical characteristics of its nephrotoxicity as well as its experimental research carried out in animal models, toxicity mechanisms and pharmacokinetics in recent years.
出处
《世界科学技术-中医药现代化》
2003年第2期31-36,77,共6页
Modernization of Traditional Chinese Medicine and Materia Medica-World Science and Technology
关键词
关地木通
肾毒性
药代动力学
毒性机理
动物模型
马兜铃酸
中药
Caulis aristolochiae manshuriensis, nephrotoxicity, aristolochia acid, animal model, pharmacokinetics
