某镉污染村居民尿镉、尿β_2-微球蛋白调查分析

Investigation of Urinary Cadmium, β_2-microglobulin in Cadmium

本文报告某污染村居民尿镉、尿β_2-微球蛋白(BMG)排出情况,同时测定了尿总蛋白量。该村糙米镉均值为0.64±0.84μg/g。居民历来以本地生长的大米为主粮。69例受检者尿镉几何均值10.4μg/g·Cr为对照村1.5μg/g·Cr的6.9倍;尿BMG几何均值181μg/g·Cr明显高于对照村104μg/g·Cr(P<0.05)。发现7例有肾小管功能障碍象征,尿BMG值在1114～13248μg/g·Cr,尿总蛋白量也有所升高。

Urinary cadmium,β2-microglobulin and total protein were measured in 69 people living in cadmium polluted village. The cadmium mean concentration of unpolished rice produced in the village was 0.64±0.84ug/g. Cr, which is the staple food of the villager all through the ages. The geometric mean value of urinary cadmium in 69 objects ( 10.4ug/g.Cr ) was 6.9 times as much as the control village (1.5ug/g.Cr ) The objects showed a geometric mean value of 181ug/g.Cr in urinary β2-microglobu-lin concentration, while the value in control people was 104μg/g.Cr, showing a statistically significant diffrence of the concentrations between the two groups ( P< 0.05 ) . Seven of them had some indications of renal tubular dysfunction, with β2-microglobulin value 1114-13248ug/g.Cr and increasing in total protein excretion.