N-(4-氯苯基)-N’-(1,2,4-三氮唑)脲的合成

The Synthesis of N-(4-chlorine phenyl) -N'- (1, 2, 4-triazoly) Urea

以 4-氯苯甲酸为原料 ,经过Curtius重排反应制得 4-氯苯异氰酸酯 ,再进一步与 3 -氨基 -1H -1,2 ,4-三氮唑发生亲核加成反应 ,合成了目标化合物N -(4 -氯苯基 ) -N’ -(1,2 ,4-三氮唑 )脲 ,其产率为 89% .对目标化合物经元素分析、IR和1 HNMR表征 ,并初步测定了此化合物的植物生长调节活性 .

N-(4-chlorine phenyl)-N'-(1, 2, 4-triazoly) Urea compound is synthesized by rearrangement reaction of 4-chlorine isocyanate and 5-amino-1,2, 4-triazole, in 80% yield. The structure of the compound is characterized by way of elemental analysis, IR and HNMR. Preliminary cytokinin-activity of the compound is determined.