静注曲马多用于预防全麻患者拔管期躁动的临床观察

Preventive effect of tramadol on agitation in the period of extubation in general anesthesia patients

目的 :研究手术结束前静注曲马多对预防全麻病人拔管期躁动的临床作用。方法 :4 0例普胸手术全麻病人 ,采用随机、双盲、对照试验的方法于手术结束前静脉给予生理盐水 (对照组 )、曲马多 2mg/kg(观察组 )观察术后病人的镇静效果。结果 :观察组与对照组比较 ,术后清醒时间、拔管时间和血氧饱合度均无显著差异。观察组镇静效果Remesay评分 :其烦躁率 ( 1分 )、镇静满意率 ( 2～ 4分 )分别为 1( 5 % ) ,15 ( 75 % ) ,对照组分别为 6( 30 % ) ,7( 35 % )。两者比较有显著差异 (P <0 .0 5 )。结论 :全麻病人手术结束前使用 2mg/kg曲马多可明显减少全麻病人拔管期躁动。

Objective:To investigate the clinical preventive effect of tramadol on agitation in the period of extubation in general anesthesia patients. Method:40 thoracic surgical patients were randomly selected to control group (normal saline iv) and tramadol (2mg/kg iv). The sedative effects were observed blindly. Results:There were no significant differences in the wakening time,extubation time and SpO 2 between control group and tramadol group.Remesay scores in control group: agitation rate (1 point), satisfactory rate of sedation (2～4 points) were 1 (5%) and 15 (75%) respectively; in control group were 6 (30%) and 7(35%) respectively. There statistical significant(P<0.05). Conclusion:In general anesthetic patients administered 2mg/kg tramadol intravenously before the end of operation reduced significantly the agitation in extubation period.