甲状腺机能亢进症患者血清干扰素水平测定的意义

The Meaning of Measurement of Serum Interferon in the Hyperthyroidism

采用微量:病变抑制法对45例甲亢患者进行了血清干扰素(IFN)水平测定。35例(77.8%)IFN≥4000IU/L,20例(44.5%)≥10000IU/L,明显高于正常人(2230±447IU/L)。16例IFN值高的甲亢患者同时测定ANAb、IgG、IgA、IgM,结果IgG高于正常。IgG、IFN的水平与甲状腺肿大有一定关系。Grave病与其他自身免疫疾病类似,IFN增高,认为IFN水平测定有可能作为观察甲亢患者免疫调节指标,值得进一步探索。

This paper reports the level of serum interferon(IFN) measured in 45 patients with Gravest disease by microdetermination. In 35 cases(77.8%) IFN≥4000IU/L & in 20 cases (44.5%)≥10000IU/L. They were obviously higher than normal people (2230±447IU/L). ANAb, IgG, IgA, IgM were measured in 16 Graves, disease with high IFN & IgG was higher than the normal. IgG & IFN level have relevance to thyroneus. IFN of Graves′ disease is increased similar to other active immune disease.The author put forward that the measurement of IFN level may be used as regulating target to observe the immunity of the patients with Graves′ disease & these data will be of some value to make further exploration.