窒息后新生儿24小时食管PH值的动态观察

Ambulatory 24 hr Oesophageal PH Monitoring in Neonates With Asphyxia.

【目的】 探讨出生窒息对新生儿胃肠运动的影响。 【方法】 用便携式 2 4hPH记录仪动态监测 3 0例不同程度窒息后新生儿和 15例对照新生儿的 2 4h食管PH值。 【结果】 窒息组反映胃食管返流的各项参数均明显高于对照组 ,其中返流指数窒息组 /对照组为 7.8/1.9,返流次数为 13 9/3 1。返流 >5min的次数 6.1/0 .9,最长返流时间 2 5 .1/4 .5 ;PH <4总时间 162 /2 1,差异均有非常显著意义 (P <0 .0 1)。重度窒息组各项返流指数明显低于轻度窒息组 (P <0 .0 1)。 【结论】 窒息后新生儿胃食管返流较对照组明显增加 。

To investigate the effects of perinatal asphyxia on gastroenteric motility of the newborn. The distal 24 hr esophageal PH monitoring was performed in 30 asphyxiated full term newborns and 17 controls using a synectics digitrapper systerm for ambulatory PH recording. The 24 hr esophageal PH monitoring revealed that the variables of acid reflux in asphyxia group were all dramatically higher than those of control.The reflux index was 7.8/1.9(asphyxia group/control group),the number of reflux episodes was 139/31,the number of reflux over 5 min was 6.1/0.9,the longist time of reflux was 25.1/4.5,the total time of PH<4 were 162/21.The differences were all significant ( P <0.001).The variables of reflux in the severely asphyxia group were all dramatically lower than those in the slightly asphyxia group( P <0.001).[Conclusions] The gastroesophageal reflux increased in the asphyxia neonates,early intervention should be given.