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重组人生长激素在烧伤治疗中的应用进展 被引量：3

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摘要 重组人生长激素(rhGH)在我国应用始于1986年对儿童GHD患者的治疗,并逐渐在外科营养及烧伤外科领域应用.目前在危重烧伤治疗中应用rhGH,取得了令人满意的效果,现将其作用机制、临床疗效、不良反应作一综述.
作者 韩焱福
机构地区 江苏省江阴市人民医院
出处 《医学理论与实践》 2003年第6期658-659,共2页 The Journal of Medical Theory and Practice
关键词 重组人生长激素 烧伤 治疗 不良反应 临床疗效
分类号 R644 [医药卫生—外科学] R977.1 [医药卫生—药品]
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参考文献10

  • 1许辉,黄跃生,彭毅志,刘旭盛,罗奇志,田学功,刘晓冰.重组人生长激素应用于烧伤治疗的临床评价[J].中华烧伤杂志,2002,18(5):288-291. 被引量：35
  • 2Jackson NC, Carrol PV, Russell DL, et al. Effect 0f glutamine supple mention, GH and IGF-1 on glutamine metabolism in critically ill patients.Am J Phsiol Endocrinal Metab,2000,278(2) :226 - 233.
  • 3Berman RS, Harrison LE, Pearlstone DB, et al. Growth hormone, alone and in combination with insulin,increase whole body and skeletal muscle protein kirtics in cancerpatients after surgery.Am Surg, 1999,229(1) : 1- 10.
  • 4Kazuya T, Fujiyo S, Robert B, et al. Recombinant growth hormone modulates Th1 and Th2 cytokine in Burned mice. Ann Surg, 1998,228:106- 111.
  • 5Edwards CK, Arkins S, Yunger LM, et al. The macrophage-activating properties of growth hormone.. Cell Mol Neurobio, 1999,12:499- 509.
  • 6Steenfos H, Spencer E, Hunt T. Insulin-like growth factor has a major role in wound healing. Sarg Forum, 1989.68 - 70.
  • 7Jorgensen PH,Ndreassen TT.The influence of biosynthetic human growth harmone on biomechanical properties of rat skin incisional wounds. Acta Chr Scand, 1988,154:623 - 626.
  • 8Gore DC, Honeycutt D, Jahoor F,et al. Effect of exogenous growth hormone on hlucose utilization in in burn patients.J Surg Res, 1991,51:518-523.
  • 9DeBoer H, Blok C.J, Vander veen EA, et al. Clinical aspect of growth hormone deficiency in aduts. EndorRov, 1995,16(1) :63 - 86.
  • 10Ishikawa M, Hiroi N, Kamioka T, et al. Metabolic effects of 20 Kda and 22Kda huma growth hormones on adult male spontaneous dwarf rats[J].Eur J Endocrinol,2001,145(6) :791 - 797.

二级参考文献10

  • 1Stephen J.Aggressive nutritional support does not prevent protein loss despite fat gain in septic intensive care patients.J of trauma,l994,27:262-266.
  • 2Takagi K,Suzuki F,Barrow,RE,et al.Growth hormone improves immune function and survival in burned mice infected with herpes simple virus type 1.J Surg Res,1997,69:166-170.
  • 3Kazuya T,Fujiyo S,Robert B,et al.Recombinant growth hormone modulates Th1 and Th2 cytokine response in Burned mice.Ann Surg,1998,228:106-111.
  • 4Edwards CK,Arkins S,Yunger LM,et al.The macrophage-activating properties of growth hormone. Cell Mol Neurobio,1999,12:499-509.
  • 5Steenfos H,Spencer E,Hunt T.Insulin-like growth factor has a major role in wound healing.Surg Forum,1989.68-70.
  • 6Jorgensen PH,ndreassen TT.The influence of biosynthetic human growth hormone on biomechanical properties of rat skin incisional wounds.Acta Chr Scand,1988,154:623-626.
  • 7Gore DC,Honeycutt D,Jahoor F,et al.Effect of exogenous growth hormone on glucose utilization in burn patients.J Surg Res,1991,51:518-523.
  • 8Horndon DN,Hawkins HK,Nguyen T,et al.Characterization of growth hormone enhanced donor site healing in patients with large cutaneous burns.Ann Surg,1995,221:649.
  • 9Jiang Z,He G,Zhang S,et al.Low-dose growth hormone and hypocaloric nutrition attenuate the protein catabolic response after major operation.Ann Surg,1989,210:513-525.
  • 10孙永华,周业平,蒋朱明,苏虹,闫汝蕴,陈忠,崔世日.生长激素在成人大面积深度烧伤的应用[J].中华整形烧伤外科杂志,1998,14(4):277-280. 被引量：25

共引文献34

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引证文献3

二级引证文献7

医学理论与实践
2003年 第6期

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