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肺癌患者运动心肺功能的特点及影响因素的观察

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摘要 目的 探讨肺癌患者运动心肺功能的特点及其可能的影响因素。方法 对20例健康者和198例助癌患者行静息肺功能、心电图和运动心肺功能测定。结果 ①与健康组相比,肺通气功能正常的肺癌患者VO2%P、VO2/kg、AT、VO2/HR%、VE、VT/VC降低,BR增加(P<0.05或0.01)。②在肺通气功能正常的情况下,周围型和中心型组间无显著性差异。③与I期肺癌患者相比,Ⅱ期患者的VT/VC、Ⅲ期患者的VO2%P、AT、VO2/HR%、VT/VC和Ⅳ期患者的VO2/HR%、VT/VC降低(P<0.05或0.01)。Ⅱ期患者的BR增高(P<0.05);Ⅱ期与Ⅲ期患者在W%、VO2%P、VO2/HR%有显著性差异(P<0.05)。④血管侵犯组的W%、VO2%P、V02/HR%较无血管侵犯组降低(P<0.05或0.01)。结论 肺癌患者在静息肺功能正常的情况下,存在着运动通气受限,并成为运动中氧摄取量减少、无氧阈提前出现的主要原因。其运动心肺功能的进一步减退与肺癌的TNM分期,特别是肺癌侵犯大血管有关。
出处 《结核病与胸部肿瘤》 2003年第2期123-128,共6页 Tuberculosis and Thoracic Tumor
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