四川省2001-2002年流行性感冒病原学及血清学监测

Surveillance of Virological and Serological of Influenza in Sichuan in 2001-2002

目的 对四川省 2 0 0 1- 2 0 0 2年流感病原学及血清学监测结果进行分析。方法 用狗肾传代细胞 (MDCK)和鸡胚双腔法进行流感病毒分离 ;用血凝抑制实验对攀枝花、雅安和德阳等 3个流感监测点的 14 3名健康人血清进行流感病毒抗体检测。结果 2年共采集流感样患者标本 1838份 ,分离出流感病毒 78株 ,其中甲1、甲3和乙型流感病毒分别为 4 0株、 3株和 35株。四川省健康人群对A/上海 / 7/ 99(H1N1)、A/福建 / 15 1/ 2 0 0 0 (H3N2 )、B/上海 / 2 0 / 2 0 0 1和B/浙江 / 2 / 2 0 0 1流感病毒的血清抗体阳性率分别是 96 5 %、 10 0 0 %、 96 5 %和 6 7 8%。结论 2 0 0 1- 2 0 0 2年四川省流感的流行情况较为平静 ,流行优势株分别为乙型和甲1亚型流感病毒。

Objective To analyze the virological and serological surveillance of influenza in Sichuan in 2001-2002 Methods The samples were isolated by MDCK cells and embryonated eggs The hemagglutination test was used to detect the antibody titers of 143 healthy persons in three districts (Panzhihua, Yaan, Deyang) Results Among 1838 samples, 78 were positive for influenza detection Of the 78 positive isolates, 40 were influenza type A(H 1N 1) viruses, 3 were influenza type A(H 3N 2) viruses and 35 were influenza type B viruses The positive rates of A/Shanghai/7/99(H 1N 1), A/Fujian/151/2000(H 3N 2), B/Shanghai/20/2000 and B/Zhejiang/2/2001 antibodies were 96 5%,100 0%,96 5% and 67 8% respectively among the population in 2002 Conlusions Influenza was not prevalent in Sichuan from 2001 to 2002 The main type were influenza type B and type A(H 1N 1) viruses respectively