膀胱癌术后化疗的疗效观察

Clinical Observation on the Postoperative Cases of Urinary Bladder Carcinomas with Serial Perfusion Prevention

目的 观察膀胱癌术后灌注化疗防治膀胱癌术后复发的疗效。方法 30例膀胱癌患者术后用丝裂霉素C(MMC) 4 0mg ,每周灌注 1次 ,共 6次后 ;再序联用卡介苗 (BCG) 15 0mg加白介素 - 2(IL - 2 ) 1.0× 10 5U ,每周灌注 1次 ,共 6次 ,此后每月灌注 1次 ,共 2年。结果 随访 2 4～ 30个月 ,平均 2 7个月 ,有效率达 93.3%。结论 MMC序联BCG加IL -

Objective To study the effectiveness on the postoperative cases of urinary bladder carcinomas with serial perfusion prevention and chemotherapy. Methods We have observed 30 cases of urinary bladder carcinomas. The procedure includes: firstly, to begin the perfusion of MMC 40 mg once a week for six weeks, and then perfuse BCG150 mg+IL-2 100 000 u once a week for six times, finally we perfuse once a month for two years;Results Having followed up the patients for 24～30 months (average 27 months),the effective rate is 93.3%.Conclusions The result shows that the measure of perfusion has effects against the recurrence of the postoperative cases of urinary bladder carcinomas.