小儿双清颗粒治疗小儿血液病伴发热的临床观察

Observation of the effects of Xiaoer Shuangqing on fever in children hematologic disorders

目的:观察小儿双清颗粒对血液病(白血病、淋巴瘤)患儿发热的疗效及不良反应。方法:比较小儿双清颗粒治疗组和对照组体温下降时间、体温波动幅度、电解质紊乱及对血小板和白细胞的影响。结果:治疗组体温波动幅度较对照组小(P<0.001);体温恢复正常时间两组无显著性差异(P>0.05);治疗组发生电解质紊乱较对照组少见(P<0.001);血小板、白细胞下降治疗组不明显。结论:小儿双清颗粒退热作用明显,无明显不良反应。

Objective: To observe the efficacy and side effects of Xiaoer Shuangqing on fever with hematologic disorders (leukemia, lym-phoma ) of children. Methods: The average of fever allaying, the range of temperature fluctuating, electrolyte and its effect on blood platelet and leukocyte were compared between the Xiaoer Shuangqing group and the conventional group. Results: The result showed that the temperature fluctuation was lesser in Xiaoer Shuangqing group compared with the conventional group ( P<0. 001) . No significant difference allaying was observed in two groups when temperature was getting back normal ( P > 0. 05). The disturbance of electrolyte and decrease of blood platelet and leukocyte did not occurs at Xiaoer Shuangqing group ( P <0. 001) . Conclusion: Xiaoer Shuangqing wes effective in pyretolysis without side-effect occurrence.