1Matsushita K,Matsuyama T,Kitagawa K,et al. Alterations of bcl-2 family proteins precede cytoskeletal proteolysis in the penumbra, but not in infarct centres following local cerebral ischemia in mice. Neurosci, 1998,83 (2): 439-448.
2Graham SH,Chen J,Clark RS. Bcl-2 family gene products in cerebral ischemia and traumatic brain injury. J Neurotrauma,2000,17(10):831-841.
3Tsujimoto Y, Cossman J, Jaffe E, et al. Involvement of the bcl-2 gene in human follicular lymphoma. Science, 1985, 228(4706) : 1440-1443.
4Shimizu S, Nagayama T, Jin KL, et al. Bcl-2 antisense treatment prevents induction of tolerance to focal ischemia in the rat brain. J Cere Blood Flow Metab,2001,21(3) :233-243.
5Zhu Y,Prehn J,Culmsee C,et al. The β2-adrenoceptor agonist clenbuterol modulates bcl-2,bcl-xl and bax protein expression following transient forebrain ischemia. Neurosci, 1999,90 (4):1255-1263.
6Bilbao F, Guarin E, Nef P, et al. Cell death is prevented in thalamic fields but not in injured neocortical areas after permanent focal ischaemia in mice overexpressing the antiapoptotic protein Bcl-2. Eur J Neurosci,2000,12(3) :921-934.
7Chen J, Graham SH,NakayamaM,et al. Apoptosis repressor genes bcl-2 and bcl-x-long are expressed in the rat brain following globalischemia. J Cereb Blood Flow Metab,1997,17(1):2-10.
8Chen J,Graham SH, Chan PH, et al. Bcl-2 is expressed in neurons that survive focal ischemia in the rat. Neuroreport,1995,6(2) :394-398.
9Ferrer I, López R, Blanco R, et al. Bcl-2, bax, and bcl-x expression in the CAt area of the hippocampus following transient forebrain ischemia in the adult gerbil. Exp Brain Res,1998,121(2) :167-173.
10Wiessner C, Allegrini P, Rupalla K, et al. Neuron-specific transgene expression of bcl-xl but not bcl-2 genes reduced lesion size after permanent middle cerebral artery occlusion in mice. Neurosci Lett, 1999 ,268(3):119-122.
6Antonawich FJ,Federoff HJ,Davis JN.Bc1-2 transduction using a herpes simples virus amplicon,protects hippocampal neurons from transient global ischemia[J].Exp Neurol,1999,156:130～ 137.
7Chen J,Graham SH,Nakayama M,et al.Apoposis repressor genes Bc1-2 and Bc1-x-1ong are expressed in the rats brain following global ischemia[J].J Ceorb Blood Flow Metab,1997,17:2～ 10.
8Hara A,Iwai T,Niwa M,et al.Immunohistchemical detection of Bax and Bc1-2 proteins in gerbil hippocampus folloeing transinent forebrain ischemia[J].Brain Res,1996,711:249～ 253.
