聚乙烯醇栓塞治疗子宫肌瘤的疗效评价

Uterine artery embolization with polyvinyl alcohol for the treatment of uterine myoma

目的 :评价聚乙烯醇 (PVA)对子宫肌瘤栓塞的疗效。方法 :子宫肌瘤 3 0例行单侧股动脉插管双侧髂内动脉及选择性双侧子宫动脉造影以了解肿瘤供血后 ,使用 PVA栓塞双侧子宫动脉并随访 3～ 3 6个月 (平均 13个月 ) ,采用 B超或 MRI考核疗效。结果 :瘤体无变化者 3例 ,完全消失者 3例 ;瘤体缩小 60 %～ 90 %者 11例 ,3 0 %～ 5 9% 13例 ;6个月复查平均比术前缩小 4.1cm (65 % ) ;临床症状消失 2 1例 ,明显改善 8例 ,无改善 1例 ,无严重并发症发生。结论 :PVA对子宫肌瘤栓塞有安全、易于注射、疗效好等优点 ,特别以选择PVA颗粒直径 3 0 0～ 5 0 0

Objective:To observe the effectiveness of uterine artery embolization with polyvinyl alcohol(PVA)in the management of uterine fibroids.Methods:Thirty patients with uterine myoma underwent bilateral uterine artery embolization with PVA.Ultrasound or MRI follow up were obtained.Results:All cases were followed up from 3 to 36 months(mean,13 months).Except for 3 cases,follow up ultrasonographic or MRI examinations showed tumor disappearance,and 60% 90% and 30% 59% reduction of tumor volume in 3,11 and 13 cases,respectively;overall,the mean fibroid volume reduction was 65% 6 months after embolization.The symptoms were completely resolved in 21,markedly improved in 8,and no change in 1 patient.There were no serious complications.Conclusion:Uterine artery embolization with PVA for the treatment of uterine fibroids is a safe and easy technique with very good clinical efficacy.