摘要
目的 探讨肝硬化患者 SICAM- 1、IL- 6和 TNF含量的变化。方法 用酶联免疫吸附法检测了 4 9例肝硬化患者血清中 SICAM- 1、IL - 6和 TNF含量 ,并以 35名正常人作对照。结果 肝硬化患者血清 SICAM- 1、IL- 6和 TNF含量均明显地高于正常人组 (P<0 .0 1) ,且与 AL T、TBil呈明显正相关。结论 检测肝硬化患者血清中 SICAM- 1、IL- 6和 TNF水平在一定程度上反映了机体的免疫功能状态。
Objective The explore the changes of serum SICAM 1?IL 6 and TNF levels in patients with liver chirrosis.Methods Levels of serum SICAM 1,IL 6 and TNF were detected by enzyme linked immunosorbent assay(ELISA) in 49 cases of liver chirrosis and 35 normal controls.Results Serum levels of SICAM 1,IL 6 and TNF were obviously higher than those in normal controls( P <0.01).There were significamly positive correlation among serum levels of SICAM 1,IL 6,TNF,serum ALT and total bilirabin.Conclusion The serum levels of SICAM 1,IL 6 and TNF in patients with liver chirrosis reflect the immune function and degree of liver cells damage.
出处
《淮海医药》
2003年第4期278-279,共2页
Journal of Huaihai Medicine
