抗菌药物引起二重感染51例报道

Superinfection Caused by Antibiotics: A 51 Case Report

目的 分析引起二重感染的原因 ,促进抗菌药物的合理使用。方法 对我院 2 0 0 1年 1～ 6月部分住院患者(5 1例 )住院期间发生的二重感染进行了回顾性研究 ,对患者年龄、原发疾病、住院天数、细菌培养结果、抗菌药物应用情况和二重感染部位和类型统计分析。结果 结果表明高龄、严重的原发疾病、长期联合使用抗菌药物尤其是广谱抗菌药物、长期住院等是引起二重感染的主要原因。结论 对高危患者临床用药过程中应注意合理选择抗菌药物及适当的给药方案 ,并观察患者的临床表现 ,以减少二重感染的发生。

OBJECTIVE To investigate the risk factors of superinfection and improve the rational use of antibiotics. METHODS The clinical data such as age, original disease, time of hospitalization, antibiotics used and the kinds of superinfection caused in 51 cases from 500 hospitalized patients were analyzed. RESULTS Age, severity of original disease, wide use of broad-spectrum antibacterial agents are the main reasons for superinfection. CONCLUSIONS In order to reduce the occurrence of superinfection, suitable antibiotics as well as dosage regimens should be chosen for high risk patients.