铜绿假单胞菌医院感染分析

Nosocomial Infection Caused by Pseudomonas aeruginosa

目的 了解铜绿假单胞菌的医院感染现状及其耐药性变化 ,为临床防治提供依据。方法 回顾分析我院2 0 0 0年铜绿假单胞菌医院感染病例 ;统计分析 1997～ 2 0 0 0年铜绿假单胞菌的耐药性变化。结果 铜绿假单胞菌感染主要发生在重症监护病房 (2 6 .1% )和呼吸内科 (2 3.2 % ) ;感染部位主要是呼吸道 (6 0 .9% )和伤口 (2 9 0 % ) ,亚胺培南、哌拉西林 /他唑巴坦和头孢他啶连续 4年耐药率均 <14 %。结论 危重患者是铜绿假单胞菌感染的易感人群 ;加强耐药性监测 ,合理应用抗菌药物十分重要。

OBJECTIVE To investigate the information about the present nosocomial infection characteristics and drug resistance of Pseudomonas aeruginosa(PA). METHODS Nosocomial infection caused by PA was retrospectively analyzed in 2000. The change in drug resistance of PA was analyzed during 1997-2000. RESULTS The main departments with nosocomial infection caused by PA happened frequently were intensive care units(26 1%) and respiration department(23.2%). The common sites were respiratory tract(60.9%) and wound(29%). The ratio of resistance for imipenem,piperacillin/tazobactam, ceftazidime against PA was less than 14%. CONCLUSIONS The acquired nosocomial infection caused by PA in critical patients more easily than in others. It is very important to select antibiotics correctly according to the results of susceptibility tests.