丰富环境早期干预对早产儿预后的影响

The effects of enriched environmental intervention on prognosis of immature infants

目的 研究早期丰富环境干预对早产儿预后的影响。方法 将胎龄 3 0～ 3 6周、出生体重 170 0～2 45 0g的 10 6例早产儿随机分为早期丰富环境干预组 (干预组 )和普通环境干预组 (对照组 ) ,生后即开始不同环境干预 ,观察对早产儿出生后 2周内呼吸、心率、神经行为评分、吸吮能力、睡眠的影响及对大运动、精细运动发育过程、语言发育过程、2岁内脑性瘫痪 (CP)发生率影响。结果 干预组出生 2周内呼吸、心率、睡眠较对照组平稳 (P <0 .0 1) ,吸吮能力较对照组强 (P <0 .0 1) ,神经行为评分高于对照组 (P <0 .0 5 ) ,干预组运动发育过程显著快于对照组 ,2岁内CP发生率显著低于对照组 (P <0 .0 1)。结论 对早产儿应尽早开始早期丰富环境干预 。

Objective To determine whether enriched environmental intervention has some effect on the prognosis of immature infants. Methods We investigated 106 infants whose gestational age was between 30-36 weeks and their birth weight ranged from 1700-2450 g. We divided them randomly into enriched environment group and normal environment group.They were put into different environment 2 weeks after birth and their respiratory rate, heart rate, Neonatal behavioral neurological assessment(NBNA), sucking ability, and sleeping were observed till 2 years old , as well as their athletic development ,language development, and morbidity of cerebral palsy. Results The infants in enriched environment group had more stable respiratory rate, heart rate, sucking ability and sleep. They also had higher NBNA accounts, quicker athletic development and lower morbidity of cerebral palsy.Conclusion Early enriched environmental intervention may improve the prognosis of immature infants.