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熊去氧胆酸在肝病中的应用 被引量:2

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出处 《医学综述》 2003年第6期362-364,共3页 Medical Recapitulate
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  • 1Dinesh K, Rakesh KT. Use of ursodeoxycholic acid in liver diseases[J] .J Gastroen Hepatol,2001,16(1) :3-14.
  • 2Benz C, Angermuller S, Tox U, et al. Effect of tauro-ursodeoxycholic acid on bile acid induced apoptosis and cytolysis in rat hepatocytes[ J].J Hepatol, 1998,28( 1 ) :99-106.
  • 3Stiehl A, Benz C, Sauer P. Mechanism of hepatoprotective action of bile salts in liver disease [ J ]. Gastroenterol Clin N Am, 1999,28 ( 1 ) : 195-209.
  • 4Rodrigues CMP,Guangsheug F,Ma X, et al.A novel role for ursodeoxycholic acid in inhibiting apoptosis by modulating mitochondrial membrane perturbation[ J]. J Clin Invest, 1998.101 (12) : 2790-2799.
  • 5Bodrigues CMP, Fan G, Wong PY, et al. Ursodeoxycholic acid may inhibit deoxycholic acid induced apoptosis by modulating mitochondrial transmembrane potential and reactive oxygen species production [ J ].Mol Med, 1998,4(3) : 165-178.
  • 6Botla R, Spivey JR, Aguilar H, et al. Ursodeoxycholate (UDCA) inhibits the mitochondrial membrane transition induced by chenodeoxycholate:A mechanism of UDCA protection[J] .J Pharmacol Exp Ther,1995,272(2) : 930-938.
  • 7Mitsuyoshi H, Nakaashima T, Sumida Y, et al. Ursodeoxycholic acid protects hepatocytes against oxidative injury via induction of antioxidants[J]. Biochem Biophys Res Commun, 1999,263(2) :537-542.
  • 8Pares A,Caballeria L,Rodes J, et al. Long term effects of ursodeoxycholic acid in primary biliary cirrhosis: results of a double blind controlled multicentric trial[ J ]. J Hepatol, 2000,3 ( 4 ) : 561-566.
  • 9Angulo P, Batts KP, Themeau TM, et al. Long term ursodeoxycholic acid delays histological progression in primary biliary cirrhosis[J]. Hepatology, 1999,29(3) :644-647.
  • 10Angulo P,Dickson ER,Therneau TM, et al. Comparison of three doses of ursodeoxycholic acid in the treatment of primary biliary cirrhosis: a randomized trial[J] .J Hepatol, 1999,30(5) :830-835.

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