沙拉沙星分子印迹聚合物的制备及其吸附特性

Preparation and Binding Characteristics of Molecularly Imprinted Polymers for Sarafloxacin

以沙拉沙星为模板分子、甲基丙烯酸为功能单体和乙二醇二甲基丙烯酸酯为交联剂合成了分子印迹聚合物 ,并用平衡吸附实验研究了其吸附性能。结果表明 :该聚合物对沙拉沙星有较高的亲和性和选择性 ,解离常数Kd=7.2 6× 10 - 7～ 2 .19× 10 - 5mol L。

Molecular imprinted polymers(MIPs) for sarafloxacin were prepared using methacrylic acid as a monomer and ethylene glycol dimethacrylate as a cross-linker. The binding capacity was studied by equilibrium binding test. The MIPs showed high affinity and specificity to sarafloxacin, with K-d = 7.26 x 10(-7) mol/L - 2.19 x 10(-5) mol/L.