心脏肿瘤30例临床病理分析

Tumors and tumor-like conditions of the heart and pericardium: a clinical pathologic analysis of 30 cases

目的 :分析 30例心脏肿瘤的病理类型、形态学变化及其临床病理特征。方法 :采用HE染色、组化及免疫组化SP技术对 30例心脏肿瘤进行病理学观察。结果 :良性肿瘤 2 5例 (83% ) ,包括心房粘液瘤、心脏横纹肌粘液瘤、心包囊肿 ;恶性肿瘤 5例 (1 7% ) ,包括血管内皮肉瘤、恶性间皮瘤、恶性淋巴瘤、心包恶性胸腺瘤及转移癌。结论 :心脏肿瘤以原发性较多见。而原发性心脏良性肿瘤以心房粘液瘤最多见 ,其他少见 ,原发性心脏恶性肿瘤类型较多 ,组织学形态较复杂 ,易与继发性肿瘤混淆。选择适当的影像学检查 ,有效的心脏外科手术、配合以病理形态学观察及免疫组化标记 。

Objective:To study histologic typing, morphologic changes and pathologic features of cardiac tumors.Methods:Thirty cases of cardiac tumors were investigated with HE staining, histochemistry and immunohistochemistry.Results:Of the tumors, 25 cases (83%) were benign tumors, including cardiomyxoma, cardiac rhabdomyomyxoma, and pericardiac cysts. Five cases (17%) were malignant tumors, including hemangioendotheliosarcoma, malignant mesothelioma, malignant lymphoma, malignant thymoma of pericardium and metastatic tumors.Conclusion:Primary cardiac tumors are common, cardiac myoxoma is the most common type of primary cardiac tumors, and other types of benign tumors were rare. Malignant counterpart of percent is complicated and sometimes difficult to distinguish from metastatic tumors. It is very necessary to choose proper image examinations, effective surgical procedures, careful pathomorphologic analysis and immunohistochemical staining for the diagnosis and treatment of primary heart tumors.