新生儿71例血样的血型血清学监测及分析

Serological Detection and Analysis on Blood Samples of Seventy-one Newborns

目的 通过新生儿血样检测及其母血清血型抗体水平调查 ,探讨诊断新生儿溶血病 (HDN)的有效方法。方法 选择 71例新生儿血样 ,采用血型血清学方法进行HDN的相关检测分析。结果 明确母婴血型不合HDN诊断 2 2例 ,可疑 1例 ,排除 4 8例 ;排除HDN组血型分布均匀 ,确诊HDN组均为A或B ,且B抗原分布为 14例 ;HDN血型血清学检出 1项阳性 9例 ,2项阳性 7例 ,3项阳性 7例 ,确诊HDN组母血清IgG抗体效价明显高于非HDN组。结论 检测新生儿血样及其母血清型抗体水平 。

Objective To discuss the effective diagnostic means to hemolytic disease of newborn (HDN) through detecting the blood samples of the newborns and the blood type antibody levels of the sera of their mothers.Methods Correlative analysis of HDN was done thiough serological means on the smples of 71 newborns.Results Out of 71, there were 22 with blood type incompatibillty, whose blood type belonged to A, of B, and 1 suspicious of blood type incompatibility. The other 48, whose blood type distribution was well proportioned, were excluded the possibility of the disorder. The mother's IgG antibody titer of the newborns with blood type incompatibility was clearly higher than that of whom without blood type incompatibility.Conclusion It is important to detect the blood samples of newborns and their mother’s blood type antibody levels so that HDN can be predicted.