β-芳甲酰丙酸的环合及同四氢噻唑-2-硫酮的反应

Cyclization of β-Aroylpropionic Acid and Its Reaction with Thiazolidine-2-Thione

由β-芳甲酰丙酸(1a～e)在乙烯酮存在下合成了5-芳基-2(3H)呋喃酮(2a～e),β-芳甲酰丙酸(1a～c)与四氢噻唑-2-硫酮在碘代-1-甲基-2-氯吡啶盐及三乙胺存在下反应合成N-芳甲酰丙酰基四氢噻唑-2-硫酮(3a～c)。

In the presence of ketene as a condensing agent, 5-arylfuran-2 (3H)-ones (2a～e) were obtained from β-aroylpropionic acids (la～c) in good yields and N-aroylpropionylthiazolidine-2-thiones (3a～c) were prepared from reaction of β-aroylpropionic acids (la～c) with thiazolidine-2-thione in the presence of triethylamine.