慢性肝炎临床与病理对照分析

Comparison analysis of the clinic parameter and the pathology in the patients with chronic hepatitis

为提高慢性肝炎临床诊断的正确性 ,按 2 0 0 0年“病毒性肝炎防治方案”对 774例慢性肝炎患者临床表现、七项血液生化学指标ALT、AST、总胆红素 (TSB)、白蛋白 (ALB)、白蛋白 /球蛋白比值 (A/G)、γ -球蛋白 (γ -G)、凝血酶原活动度 (PTA)及门静脉内径 (MPV)、脾静脉内径 (SPV)、脾厚与病理对照分析。结果临床表现如乏力、腹胀、纳差、恶心、厌油、黄疸、鼻 /牙龈出血、蜘蛛痣及血液指标ALT、TSB、PTA、ALB、A/G均能较好反映肝组织炎症活动程度 ,PTA、ALB、γ -GT、A/G能较好反映肝纤维化进程 。

To raise the accuracy of the chronic hepatitis.According to'2000's program on prevention and treatment of viral hepatitis',the clinical manifestation,seven biochemistry indexes (ALT,AST,TSB,ALB,A/G,γ-GT and PTA),main portal vein bore (MPV),spleen vein bore (SPV),the thick of spleen and the pathology in 774 patients with chronic hepatitis were studied. It was suggested that the clinical manifestation,such as inertia,abdominal distention,anorexia,nausea,dislike of grease,jaundice,ansal/gingival bleeding and spider nevus,activity degree of hepatitis,PTA,ALB,γ-GT and A/G,were useful indexes to the development of hepatic fibrosis,and the thick of the spleen was a sensitive index to early fibrosis.