复式冲击波组织损伤的实验研究

An experiment study on tissue injury with double shock wave

目的 探讨复式冲击波对组织损伤的作用程度。 方法 采用活体猪进行系列液电式复式冲击波与单式冲击波以及电磁式冲击波冲击 ,对比分析组织损伤范围及组织学改变。 结果 8kV冲击 10 0 0次条件下 ,单式冲击波与复式冲击波肾脏损伤范围分别为 18mm× 15mm× 3mm和14mm× 11mm× 2mm ,输尿管损伤范围分别为 4 2mm和 30mm。病理检查显示 ,复式和单式冲击波对肾脏及输尿管的各层结构都可造成以出血为特征的可逆性损伤 ,很少产生瘢痕组织。与电磁式冲击波比较 ,复式冲击波碎石效果更好 ,并不增加组织的损伤。 结论 与液电式单式冲击波和电磁式冲击波相比 ,复式冲击波并不增加肾和输尿管组织损伤。

Objective To study whether tissue injury could be increased by double shock wave while it improves the efficiency of lithotripsy. Methods A series of experiment study on the tissue injury in vivo pigs with double and single shock wave as well as electromagnetic shock wave has been carried out. Results Under the conditions of 8 kV and 1 000 times concussion, the trauma range of kidney is 18 mm×15 mm×3 mm with single shock wave,and 14 mm×11 mm×2 mm with double shock wave,the trauma range of ureter is 42 mm with single shock wave and 30 mm with double shock wave.Under the same energy and concussion,the injury focus induced by double shock wave is small than that induced by single shock wave.Microstructure pathology shows that the characteristics of focus on renal artery,vein,glumeruli,renal tubules and ureter are similar. Conclusions Compared with the focus induced by single or by electromagnetic shock wave,the focus on the tissue of kidney and ureter induced by the double shock wave is smaller.