在体微透析技术应用于神经药动学研究进展
摘要
目的 :综述目前在体微透析技术应用于神经药动学研究的实验室及临床结果。方法 :检索近 10年文献 ,综述评价。结果 :微透析技术在作用于中枢神经系统药物动力学研究中具独特优势。结论 :微透析技术在药物研究中具有极其重要、广泛的实用价值及应用前景。
出处
《中国医院药学杂志》
CAS
CSCD
北大核心
2003年第6期362-364,共3页
Chinese Journal of Hospital Pharmacy
参考文献25
-
1Scheyer RD,During M J, Hochholzer JM. Phenytoin concentrations in the human brain: an in vivo microdialysis study[J ]. Epilepsy Res, 1994,18(3) :227.
-
2Scheyer RD, During MJ, Spencer DD, et al. Measurement of carbarnazepine and carbamazepine epoxide in the human brain using in vivo microdialysis[ J ]. Neurology, 1994,44(8) : 1469.
-
3Walker MC, Alavijeh MS, Shorvon SD, et al. Microdialysis study of the neuropharmacokinetics of phenytoin in rat hippocampus and frontal cortex[J]. Epilepsia, 1996,37(5) :421.
-
4Desrayaud S, Guntz P, Scherrmann JM, et al. Effect of the P-gly-coprotein inhibitor, SDZ PSC 833, on the blood and brain pharmacokinetics of colchicines[J ]. Life Sci, 1997,61 (2) : 153.
-
5Scism JL, Powers KM, Artru AA, et al. Probenecid-inhibitable efflux transport of valproic acid in the brain parenchymal cells of rabbits:a microdialysis study[J]. Brain Res,2000,884(1) :77.
-
6Wang Y, Welty DF. The simultaneous estimation of the influx and efflux blood-brain barrier permeabilities of gabapentin using a microdlalysis-pharmacokinetic approach [ J ]. Pharm Res, 1996, 13(3):398.
-
7Nakamura K, Shirane M. Activation of the reticulothalamic cholinergic pathway by the major metabolites of aniracetam[J ]. Eur J of Phamacol, 1999,380(2) :81.
-
8Cheng FC, Tsai TFI, Wu YS, et al. Pharmaeokinetic and pharma-codynamic analyses of trazodone in rat striatum by in vivo microdialysis[J] .J of Pharm Biomed Anal, 1999,19:293.
-
9Tsai TH, Chen CF. Measurement and pharmacokinetic analysis of buspirone by means of brain microdialysis coupled to high-perfor-mance liquid chromatography with electrochenaical detection[ J ]. J Chromatogr A, 1997,762( 1 ) : 269.
-
10Delange EC, Danhof M, Deboer AG, et al. Critical factors of intracerebral microdialysis as a technique to determine the pharma-cokinetics of drugs in rat brain[J]. Brain Res, 1994,666 (1) : 1.
-
1王天琳,吴春福.在体微透析结合HPLC测定小鼠纹状体细胞外尿嘧啶含量[J].实用药物与临床,2011,14(1):41-42.
-
2刘会臣,侯艳宁.在体微透析技术及其在临床药理学中的应用[J].中国临床药理学杂志,1999,15(2):138-140. 被引量：6
-
3关卫文,刘伟光,张国烈,司徒伟勤.临床一线抗高血压药应用浅评[J].中国现代药物应用,2016,10(9):270-271.
-
4李征.染料木黄酮生物学功能的研究进展[J].环境与健康杂志,2008,25(3):279-281. 被引量：10
-
5叶金朝,叶菲武.心房纤颤的抗心律失常药物临床应用评价[J].药物流行病学杂志,2004,13(5):234-236.
-
6苏芥.抗乙型肝炎病毒核苷类似物的耐药机制[J].中外医疗,2008,27(13):75-75.
-
7殷桃花.浅谈抗乙型肝炎病毒核苷类似物的耐药机制[J].亚太传统医药,2007,3(8):34-35.
-
8张恒义,王恩禹,王绪平,郁秀华.一种基于多通道微透析技术的药物小肠吸收能力评价在体实验新方法[J].中国药学杂志,2012,47(8):653-654. 被引量：2
-
9朱林,朱家壁.微透析取样技术及其在药代动力学中的应用[J].国外医学（药学分册）,2002,29(5):296-301. 被引量：2
-
10李超,胡晋红.在体微透析技术研究低相对分子质量肝素凝胶经皮给药大鼠体内药动学特征[J].中国药学杂志,2015,50(21):1899-1904. 被引量：1
