磁分离酶联免疫法测定多囊卵巢综合征患者血清性激素的结果分析

Analysis of serum sex hormone levels assayed by MAIA technology in PCOS patitents

目的 :研究磁分离酶联免疫测定 ( MAIA)技术在临床诊断多囊卵巢综合征 ( PCOS)中的应用价值 ,建立我科生殖内分泌的临床正常参考值范围。方法 :采用 MAIA技术检测 72例 PCOS患者及 10 0例对照的血清性激素水平 ,并对其结果进行分析。结果 :早卵泡期性激素 6项的 95 %正常参考值范围 :促卵泡生成素 ( FSH) :3 .3 9～ 11.3 5 IU/L ,促黄体生成素 ( LH) :1.62 IU/L～ 5 .18IU/L 泌乳素 ( PRL) :3 .62 μg/L～ 2 3 .72 μg/L,雌二醇 ( E2 ) :10 .61ng/L～ 3 4.5 3 ng/L ,孕激素 ( P) :0 .3μg/L～ 2 .82μg/L ,睾酮 ( T) :0 .0 2μg/L～ 0 .5 2μg/L ,PCOS患者与对照组比较 ,血清 LH、T水平明显增高。结论 :用 MAIA法检测血清性激素水平 ,对 PCOS的诊断有较高的可靠性。

Objective:To study the value of MAIA technology in clinical diagnosis of PCOS and establish the normal range of our lab.Methods:Serum sex hormone of 72 patients with PCOS and 100 controls were assayed by MAIA technology.Results:Sex hormone normal range:FSH:3.39～11.35mIU/L,LH:1.62～5.18IU/mL,PRL:3.62～23.72 μg/mL,E 2:10.61～34.53 μg/L,P:0.36～2.82 μg/L,T :0.02～0.52 μg/L.PCOS patients had an significant increase of serum LH and T l evels compared with controls.Conclusions:MAIA technology is a credible method f or the diagnosis of PCOS.