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采用低蛋白饮食并α酮酸治疗在延缓慢性肾功能不全进展的作用 被引量:4

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摘要 目的 观察低蛋白饮食加α酮酸制剂是否具有延缓慢性肾功能不全患者肾功能减退、改善酸中毒的疗效。方法 观察未行透析的慢性肾功能不全患者26例,采用低蛋白饮食加α酮酸制剂平均28个月后,患者肾功能、血常规、电解质、肝功能以及内生肌酐清除率(Ccr)的改变。结果 治疗后患者血常规、电解质、肝功能无明显改变,血肌酐值虽然较治疗前上升但无统计学意义,而血碳酸氢盐水平较治疗前显著升高(P<0.05)。结论 慢性肾功能不全患者长期采用低蛋白饮食加α酮酸制剂具有保护残余肾功能的作用,可减慢肾功能恶化速度,部分纠正酸中毒。
出处 《临床肾脏病杂志》 2003年第2期55-57,共3页 Journal Of Clinical Nephrology
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