中药外用治疗宫颈糜烂的临床研究

Clinical Study of External Application of Herbal Medicine for Cervical Erosion

【目的】总结中成药冰碘散、冰竭散及祛腐生肌膏治疗宫颈糜烂的疗效。【方法】采用随机对照单盲法,将140例宫颈糜烂患者分3个治疗组(冰碘散组36例、冰竭散组35例、祛腐生肌膏组36例)及西药爱宝疗栓对照组33例,4组均于月经干净2～3d后开始局部上药,隔天1次,20d为1个疗程,观察各组疗效。【结果】总有效率冰碘散组及冰竭散组与爱宝疗栓组比较差异无显著性,祛腐生肌膏组则差于爱宝疗栓组。对于轻度、中度或单纯型的宫颈糜烂,3组治疗组与爱宝疗栓组差异无显著性。对于颗粒型或乳突型宫颈糜烂,冰碘散组与冰竭散组优于爱宝疗栓组。对于重度宫颈糜烂,冰竭散组优于爱宝疗栓组。【讨论】冰碘散、冰竭散及祛腐生肌膏治疗宫颈糜烂有较好的疗效,其中冰碘散、冰竭散疗效尤佳。

[Objective] To evaluate the therapeutic effect of Bingdian Powder (BDP), Bingjie Powder (BJP) and Qufu Shengji Ointment (QSO) for cervical erosion. [Methods] A single-blind randomized controlled trial was applied. One hundred and forty cases of cervical erosion were randomized into four groups: BDP group ( n = 36) , BJP group ( n -35), QSO group ( n = 36) and Aibaoliao Suppository (AS) group ( n - 33). Local external application of medicine was carried out 2 ~ 3 days after menstrual period, one time every other day, 20 days being a treatment course. [ Results ] The total effective rate in BDP group and BJP group was similar to that in AS group and that in QSO group was lower to that in AS group. The effects of BDP, BJP and QSO for mild, moderate or simple cervical erosion were the same as that of AS group; for granular or papillary erosion, the effects of BDP and BJP were superior to those of AS, and BJP had a better effect than AS for severe erosion. [Conclusion] BDP, BJP and QSO exert good effects for cervical erosion, and BDP and BJP in particular.