急性ST段抬高心肌梗死直接经皮冠脉介入治疗对QT离散度的影响

Effect of direct percutaneous coronary intervention on QT dispertion in patiants with ST-segment elevation myocardial infarction

目的 探讨直接经皮冠脉介入治疗 (PCI)对急性ST段抬高心肌梗死患者QT离散度(QTd)的影响。方法 选择 48例成功实施了直接PCI术的急性ST段抬高心肌梗死患者为治疗组 ,选择 6例直接急诊PCI术失败未能行早期再灌注的急性ST段抬高心肌梗死患者为对照组 ,分别记录术前半小时与术后即刻、术后 3小时、术后 6小时、术后 2 4小时、第 3天、第 7天的十二导联心电图 ,计算各时期的QTd。结果 急性ST段抬高心肌梗死直接PCI治疗后 6小时QTd即明显下降 (P <0 .0 1) ,术后2 4小时下降至高峰 ,此后维持稳定。治疗组术后 6小时以后QTd较对照组有显著下降 (P <0 .0 1)。结论 直接PCI术治疗急性ST段抬高心肌梗死 ,可使患者QTd明显缩短。

Objective To study the effect of direct percutaneous coronary intervention (PCI) on QT dispertion (QTd) of patients with ST-segment elevation myocardial infarction. Methods We analysed the QTd of standard 12-lead electrocardiogram of 48 patients with ST-segment elevation myocardial infarction before and after successful PCI , compared with 6 patients with ST-segment elevation myocardial infartion after unsuccessful PCI and no reperfusion therapies. Results The QTd was significantly reduced six hours to twenty-four hours after successful PCI (P<0.01). Conclusion Successful PCI could reduce QTd significantly in patients with ST-segment elevation myocardial infarction .