激光极化技术制备核磁共振探针的方法和应用原理

The Methods of Preparing Nuclear Magnetic Resonance Probe with Laser Enhanced Polarization Technology and its Applied Theory

通过激光增强核自旋极化技术,可以得到很高的非热平衡极化度和长驰豫时间的惰性气体(129Xe和3He),其作为核磁共振探针,具有广泛的生物医学应用价值。该文探讨了激光增强129Xe和3He核自旋极化的磁共振成像和波谱学原理,介绍了激光极化惰性气体的设备和方法,以及极化气体的收集贮存和输入过程,最后对氢核及极化核的磁共振成像、极化气体129Xe和3He的应用进行了比较性总结。

Through the technology of laser enhancement and nuclear spin exchange, obtained the noble gas of 129Xe and3He with large nonequilibrium nuclear polarization and long relaxation time. As nuclear magnetic resonance(NMR) probe, they have broad applied foreground in biomedicine field. This article review the theory of laser polarized noble gases in NMR and methods of its preparation and instrument. Introduced the progress of storage?transport and injecting on the polarizedgas. And comparatively summarized the application of hydrogenous and polarized nuclear magnetic resonance?129Xe and3He.