图形视觉诱发电位最佳刺激模式的探讨

The best stimulating mode of pattern visual evoked potential

目的 在各种刺激模式的视觉诱发电位记录中,寻找一种能获取最大反应的刺激参数的组合。方法 记录5例正常人10眼不同时间频率、不同棋盘格大小和不同颜色光刺激的瞬态及稳态P-VEP,分析比较不同刺激方式组合的P100波幅值及峰潜时,找出所有组合中获得波幅值最大,峰潜时最接近100ms的一组。结果 瞬态记录,时间频率为2Hz、棋盘格大小16×12、刺激颜色为黑-白转换时所获得的P100波幅值最大,并且峰潜时最接近100ms。稳态记录时,时间频率8.5Hz、棋盘格大小16×12、刺激颜色为黑-白转换时P100波幅值最高,而时间频率8.5Hz、棋盘格大小32×24、刺激颜色为黑-白转换时峰潜时最接近100ms。结论 瞬态P-VEP记录时,时间频率2Hz、棋盘格大小16×12、刺激颜色为黑-白转换为最佳刺激模式的组合。因记录稳态P-VEP时,主要的临床指标为其P波幅值。因此,时间频率8.5Hz、棋盘格大小16×12、刺激颜色为黑-白转换为最佳刺激模式的组合。

Aim To probe into the best stimulating mode combination of pattern visual evoked potential (P-VEP). Methods We recorded the transient and steady-state P-VEPs in different timing frequencies, in different pattern sizes and in different light wave lengths in 5 normal young men (10 eyes), and compared the amplitudes and the implicit time of P100 in different modes to find the mode in which the amplitude was the highest and the implicit time was closest to 100 ms. Results By recording the transient P-VEP, we got the highest amplitude and the implicit time closest to 100 ms by the combination of timing frequency 2Hz, pattern size 16×12 and black-white transition. As for the steady-state P-VEP, the amplitude was the highest in timing frequency 8.5Hz, pattern size 16×12 and black-white transition, while the implicit time was closest to 100 ms when the combination was timing frequency 8.5Hz, pattern size 32×24 and black-white transitioa Conclusion In the transient P-VEP, the best combination is timing frequency 2Hz, pattern size 16x 12 and black-white transition, while in the steady-state P-VEP, because the amplitude of the P wave is more useful to the diagnosis, its best combination is timing frequency 8.5Hz, pattern size 16×12 and black-white transitioa